Liquid-phase Electron Microscopy for microtubule dynamics

bio 

Besides microtubules and cleanroom fabrication, I am a big fan of Open Science and Open Harwdare. I try to promote the publication of lab hardware and 3D printed items and raw datasets. If you have ideas about data management and or open hardware i'd love to talk to you about it. Outside work, I love working on all sorts of fabrication and art methods (3D-printing, casting, screen printing and etching).

Project summary 

We make custom nano- and microfluidic chips in the TU Delft Cleanroom. In this project we study both the altered dynamics of microtubules under confinement. Special variants of the chips are for liquid phase electron microscopy and we are looking to use them to image biological material inside the electron microscope in liquid water. 

Picture of a 4-inch silicon wafer with nanofluidic chips.

Nanofluidic chip mounted in a machined interposed that allows microfluidic tubing to be interfaced with the chips.